Persantine Thallium

This test is for people who are unable to exercise at an adequate level on a treadmill. It assesses the extent of coronary artery disease.

With a physician present, the patient is monitored for blood pressure, heart rate and rhythm (EKG). An IV is established and a medication called Persantine is infused over a short period of time. After this, a mild isotope is injected. The patient is then escorted to the scanning room adjacent to the stress lab for approximately 30 minutes. The patient will then be free to leave and will return 3 hours later for a repeat scan.

1.5 hours in the Cardiovascular Department followed by a 3-hour break and a 30-minute repeat scan.


  • Wear loose clothing for exercising (tennis shoes, shorts, etc.)
  • No caffeine on the day of the exam
  • Nothing to eat or drink 6 hours prior to exam (You may have water)
  • Avoid the use of creams and lotions on the chest area
  • Take your usual medications unless instructed otherwise by your physician--please bring a list of medications with you
  • No smoking on the day of the exam
  • Diabetic patients are encouraged to ask their physician for instructions when diet or medication changes are requested
  • Patients should avoid all Theophylline-based medications for 72 hours prior to the test such as:
    • Theo-bid
    • Theodur
    • Aminophylline
    • Elixophylline
    • Theolair
    • Slo-bid

If you have questions about preparing for this test, call your doctor or MyMichigan's Cardiovascular Department at (989) 839-3570.

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